Classification of myasthenia gravis and congenital myasthenic syndromes in dogs and cats
نویسندگان
چکیده
منابع مشابه
Morphologic and immunopathologic findings in myasthenia gravis and in congenital myasthenic syndromes.
Overwhelming evidence now supports Simpson's concept, originally proposed in 1960, that acquired myasthenia gravis (MG) is an autoimmune disease in which antibodies are directed against the nicotine postsynaptic acetylcholine receptor (AChR).1 An autoimmune pathogenesis of acquired MG implies that those myasthenic syndromes which occur in a congenital and familial setting may have a different, ...
متن کاملCongenital myasthenic syndromes and myasthenia gravis are challenging diagnoses in neurological practice.
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O 29: Autoimmune Myasthenia Gravis Introduction, Immunopathogenesis and Classification
Autoimmune Myasthenia Gravis (MG) is a unique disease among all autoimmune disorders in two ways. First, there are a wide range of sub-specialties involved in the diagnosis and management of MG; secondly MG is an autoimmune disorder whose autoimmunity is well established. In this paper I will cover these topics: history and epidemiology of MG followed by a brief overview on physiology of neurom...
متن کاملCongenital myasthenic syndromes.
Congenital myasthenic syndromes are a rare group of heterogeneous disorders affecting neuromuscular transmission. Recent identification and in-vitro functional analysis of some of the genetic mutations that cause these disorders correlates with previous electrophysiological, biochemical, pathological and therapeutic studies, and has advanced our understanding of neuromuscular transmission.
متن کاملCongenital myasthenia gravis.
Congenital myasthenia gravis is caused by genetic mutations affecting neuromuscular transmission, characterized by muscle weakness usually starting in childhood. A two and a half years old male child presented with bilateral ptosis and hoarseness of voice. The symptoms progressed giving the clinical impression of congenital myasthenia gravis. A series of tests were done including Ice Pack Test,...
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ژورنال
عنوان ژورنال: Journal of Veterinary Internal Medicine
سال: 2020
ISSN: 0891-6640,1939-1676
DOI: 10.1111/jvim.15855